26 results
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Features of hematologic ... predominant immature cells ... #Algorithm #hematology ... #WBC #Leukemoid
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
- Differential Diagnosis ... Chronic myelogenous leukemia ... pancytopenia, blast cells ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Lymphoblastic Leukemia ... Reed-Sternberg Cells ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Pathophysiology: ... germinative skin cells ... Skin-homing T-cells ... Dermatology #Rash
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Skin: - CLL cells ... smear: Smudge cells ... or basket cells ... #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Rapidly rising blast cells ... : Granulocytic cells ... organs When Cancer Cells ... #Hematology #Oncology ... #Diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... #Differential #diagnosis ... #hematology #eosinophilia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... = funny-shaped cells ... 10,000 new cases diagnosed ... transformation to acute leukemia ... Management #treatment #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... Chronic myeloid leukemia ... #Differential #Diagnosis ... #causes #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... Lymphocyte - 5% RS cells ... (LP) tumour B cells ... Treated Like Acute Leukemias ... #Hematology #Diagnosis