13 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... per μL • Diagnosis ... Antimicrobial treatment ... opportunistic #InfectiousDiseases ... #Neurology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Perforation) Pathophysiology ... Bezlotoxumab 10 mg/kg IV ... Treatment Guideline ... #management #treatment ... #infectiousdiseases
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... Diagnosis: MRI ... and with low CD4 ... Treatment: • HAART ... treatment • Cognitive
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 2 hit mechanism ... : 33% • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... : • CBC - Leukocytosis ... antibiotics once stable ... hemorrhage • Treatment ... shows a small, stable
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Release from blast cells ... • Steroids: IV ... #management #hematology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Elimination (see Table ... Drives K+ into cells ... #Hyperkalemia #Diagnosis ... #potassium #nephrology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Infection - Viral (HIV ... kidney tubular cells ... per day until stable ... #nephrology