79 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Cytokines, Mast Cells ... perivascular inflammatory cells ... Vasculitis #HUV #Pathophysiology ... #Rheumatology
Treatment Algorithm for First Time Pulmonary Embolism
 • Provoked
 • Unprovoked
 • Active Malignancy

By Carlin Rooke,
Treatment Algorithm ... for First Time Pulmonary ... #PE #Pulmonary # ... Embolism #Treatment ... Algorithm #management #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
(LP) tumour B cells ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Balloon Visualization - Mechanical Ventilation Pressures - PIP, PPlat, PEEP

Peak Inspiratory Pressure (PIP): Dynamic pressure needed
#PPlat #PEEP #CriticalCare ... Diagnosis #Balloon #Pathophysiology ... #Pulmonary
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... transfusion • Pathophysiology ... , and CXR with pulmonary ... : No • Treatment
Pulmonary Embolism Treatment
Systemic Thrombolysis
 - Exclude contraindications.
 - Indications:
   - Massive PE (definite indication)
Pulmonary Embolism ... Treatment Systemic ... @nickmmark #Pulmonary ... #Embolism #Treatment ... AcutePE #Management #CriticalCare
Severe Asthma Exacerbation
Signs of a Severe Asthma Exacerbation:
 • Vitals: ↑HR ↑RR ↓SpO2
 • High work
of baseline Treatments ... #Exacerbation #CriticalCare ... #pulmonary #ventilation ... mechanical #management #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells ... diagnosis #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Release from blast cells ... Imaging: CXR- pulmonary ... Renal Failure Treatment
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
• Obstructive: Pulmonary ... Dehydration Shock Treatment ... Differential #Diagnosis #criticalcare ... #algorithm #treatment