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diagnosis management oncology causes symptoms workup classification disorders hemolytic deficiency disease erythematosus lupus mds myelodysplastic pancytopenia sle systemic thrombocytopenia thrombocytosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... , Vasculitides, ... #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm ... Signs of anemia ... #Differential # ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Diagnosis Algorithm ... hepatomegaly • Labs: anemia ... predominant immature cells ... #hematology #WBC
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Diagnosis Algorithm ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... #Differential # ... Diagnosis #Algorithm ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... #Diagnosis #hematology ... #rheumatology #
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... • Sickle cells ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
recurrent fevers, vasculitis ... • Hematologic ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic ... Autoinflammatory #Somatic #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... #Causes #Hematology
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