13 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Fatigue • Acute ... Lymphocytes) - Monoclonal ... Reed-Sternberg Cells ... #Causes #Hematology ... #Oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
tubulopathy • Monoclonal ... change disease • Hematologic ... malignancies Treatment ... #AKI #Cancer #Oncology ... Differential #Diagnosis #Classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Responsive to Treatment ... Treated Like Acute ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... Kawasaki, Nephrotic syndrome ... Differential #Diagnosis #Algorithm
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transformation to acute ... only curative treatment ... #hematology #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... -95% of cases) Classification ... Treatment • Early ... #diagnosis #classification ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... or acute leukemia ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... to large cell lymphoma ... fludarabine) 3) Monoclonal ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Release from blast cells ... diagnosis #management #hematology ... #oncology