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hematology management causes lad classification focal hodgkins leukemia localized lymphoma mds myelodysplastic thrombocytosis activation anemia aplastic apml cancer chronic cll
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Diagnosis Algorithm ... Inflammatory / Infectious ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Diagnosis Algorithm ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
- Differential ... Diagnosis Algorithm ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... Rebound effect from treatment ... #Diagnosis #Algorithm ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... cell transplant is ... #Management #treatment ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelofibrosis Infectious ... effect following treatment ... #Diagnosis #Algorithm ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... (NHL) ~60% - lymphadenopathy ... more diffuse, can ... pathophysiology #Hematology ... algorithm
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL is ... weeks without infection ... microglobulin Treatment ... #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
lymphoma that is ... disease: B symptoms, lymphadenopathy ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
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