35 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... index < 2 • EPO Level ... #Anemia #oncology ... #hematology #diagnosis ... #management
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... if neutropenic fever ... progress to MDS or acute ... Anemia #diagnosis #management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... transformation to acute ... #treatment #hematology ... #oncology
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Differential Diagnosis ... Mono (EBV, CMV), Acute ... Medicine @SCVMCMed #Fever ... #Diagnosis #dermatology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... death Neutropenic Fever ... Hyperuricemia • Acute ... #differential #
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... change disease • Hematologic ... #AKI #Cancer #Oncology ... #Differential # ... Classification #Nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... : • Common: fever ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... - APLS • Acute ... Gardner-Diamond syndrome ... mountain spotted fever
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... fibrosis - Acute ... Mediterranean fever ... Causes #diagnosis #differential ... #hepatology #SAAG