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diagnosis rheumatology causes erythematosus pain arthritis dermatology management msk classification oncology algorithm cardiology criteria disease leukemia monoarticular pulmonary signs symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... : Fever (50%), Depression ... phenomenon (20%) Joints ... Demyelinating syndromes ... #SLE #systemic
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... fever • Mononeuritis ... • New murmur, fever ... #pain #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Constitutional domain: Fever ... , Acute cutaneous ... in at least 2 joints ... Classification #Criteria #SLE ... #Systemic #Lupus
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
• Rheumatic Fever ... Lupus Erythematosus ... Sicca) Syndrome ... • Rheumatic Fever ... Acute Onset
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #rashes #differential
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... [SLE], AOSD) •
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
rheumatic fever ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... approach #workup ... #differential #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... permanent alopecia Differential ... to: Arthritis, Fever ... #Systemic #Lupus
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... CLINICAL CRITERIA - ACUTE ... INVOLVING 2 OR MORE JOINTS ... #SLE #Lupus #Erythematosus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... Lupusreference #SLE ... #Systemic #Lupus ... #rheumatology
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