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diagnosis management causes erythematosus sle infections systemic hematology joint pain signs classification oncology pulmonary treatment aids algorithm arthritis cns comparison
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Malar rash 40% - Fever ... (aPL) 30-45% Differential ... autoantibodies #signs #symptoms ... #mimickers #differential ... #rheumatology
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
Constitutional: Fever ... exertion • Neurologic ... Subcutaneous nodules, lupus ... Sarcoidosis #Diagnosis #Symptoms
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Constitutional domain: Fever ... Acute cutaneous lupus ... least 2 joints • Neurologic ... Erythematosus #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: Fever ... Thrombocytopenia #Lupus ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Typical Signs/Symptoms ... Alopecia, Fever ... Adenopathies, Lupus ... Erythematosus #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
proximal joints, Fever ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
symptoms, fever ... ) • Headache, fever ... Meningitis: • Fever ... Tuberculosis #diagnosis #differential ... #TB #neurology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
• Rheumatic fever ... lesions • Discoid lupus ... #skin #rashes #differential ... #diagnosis #rheumatology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... the face (many differential ... pericarditis » is...lupus ... 9) Unexplained fever ... erythematosus #rheumatology
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Pericardial Effusion - Differential ... Non-Infectious: • Rheumatologic ... Mediterranean Fever ... Pericardial #Effusion #Differential ... Diagnosis #Causes #cardiology
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