63 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... fraction < 20% Differential ... Diaqnoses: • Infectious ... hepatitis • Pulmonary ... #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Hyperthyroidism Fever ... • Rheumatic fever ... SLE, Rheumatic fever ... stenosis - Rheumatic fever ... • New murmur, fever
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... inclusions - If infection ... bartonella (oroya fever ... Diagnosis #Algorithm #workup ... #hematology #testing
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Hyperkalemia Pulmonary ... Diptheria • Typhoid fever ... Acute rheumatic fever ... Psittacosis • Q fever ... • Yellow fever
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... susceptibility, infectious ... : High spiking fever ... Systemic AOSD: high fever ... #AOSD #rheumatology
Aortitis - Diagnosis and Workup
Clinical History:
 - Fever, weight loss, deterioration of general health
 - Aortic
Diagnosis and Workup ... Clinical History: - Fever ... on the cause Infections ... Inflammatory diseases ... #Differential #
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... • Autoimmune diseases ... Unknown cause Treatment ... #summary #rheumatology
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Diagnosis Infectious ... : • Rheumatologic ... Mediterranean Fever ... : EGPA, Horton Disease ... , Takayasu Disease
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... symptomatology Differential ... allopurinol), Infection ... DAH, rule out infection ... Renal #Syndrome #differential