23 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
hepatic crisis: • Fever ... Supportive with treatment ... cholestasis: • Fever ... Hepatobiliary #hepatology ... #differential #diagnosis
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... Inflammation: high fever ... TREATMENT: ​• Acute ... gabrieltalledop #Oroya #Fever ... #diagnosis #management
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... Framework HEMATOLOGIC ... death Neutropenic Fever ... Hyperuricemia • Acute ... #differential #diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... if neutropenic fever ... progress to MDS or acute ... #management #treatment ... #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
explain symptoms • Fever ... At least 3 of (Acute ... pulmonary edema) • Fever ... #diagnosis #comparison ... #table
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... : • Common: fever ... Renal Failure Treatment ... #management #hematology ... #oncology
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
confusion and fever ... This is relapsing fever ... Syndrome: 3d of fever ... Fever recurs over ... worsening of fever
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever ... #dermatology #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presents as an acute ... following: • Fever ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... syndrome): - Hematologic ... or HSCT - CRS: fever ... therapy - Symptoms: fever