73 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... of liver disease ... Idiosyncratic #differential ... #gastroenterology
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
• Signs and symptoms ... unresponsive to treatment ... • Elevated liver ... microscopic colitis Differential ... Diagnosis #Algorithm #gastroenterology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... : Fever, Arthralgia ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Croup Diagnosis and Management Pearls
Common childhood illness, usually viral and self limiting. Characterised by a seal-like
hoarse voice +/- fever ... rhinorrhea, and fever ... cyanosis, decreased level ... Treatment: Single ... #pediatrics #peds
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... months without treatment ... disease, liver ... Cirrhosis #Hepatology #gastroenterology ... #management #diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... the chest/trunk Symptoms ... Daily high spiking fever ... - Fever spikes ... Fever of at least
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... - Pel-Ebstein fever ... Noncontiguous spread • Clinical ... involvement Differential ... oncology #diagnosis #differential
Pneumocystis jirovecii Pneumonia 
Clinical 
 • Caused by Pneumocystis jirovecii (formerly carinil) 
 • Immunocompromised host
jirovecii Pneumonia Clinical ... CD4 < 200 • Symptoms ... 2—3 weeks • Fever ... often elevated Treatment ... Pneumonia #Diagnosis #Management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Clinical ... : • 80% have fever ... decubitus - air fluid level ... Intervention: - Fevers ... Lung Abscess Differential
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
Diagnosis and Management ... Ulceroglandular: Fever ... eye; unilateral symptoms ... Culture & GS, PCR Treatment ... : • Severe Disease