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differential management cardiology algorithm treatment classification erythematosus lupus oncology sle workup comparison dermatology hemolytic hemophagocytic hlh infectiousdiseases lymphohistiocytosis syndrome systemic
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... : • Liver disease ... • Transfusion reactions ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... mountain spotted fever ... • Drug reactions ... #hematology #rheumatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Diagnosis: • Pancytopenia ... if neutropenic fever ... #diagnosis #management ... #treatment #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... for Anemia (Morphological ... : Alcohol use, Liver ... #differential #diagnosis ... #causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Other: Transfusion reaction ... Extravascular #Causes ... #hematology #anemia
Systolic Murmurs - Differential Diagnosis Algorithm Benign / Flow / Hyperdynamic: • Pregnancy • Fever • Anemia Supravalvular
Pregnancy • Fever ... • Anemia Supravalvular ... • Rheumatic Fever ... • Rheumatic Fever ... • Rheumatic Fever
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... without other cause ... explain symptoms • Fever ... pulmonary edema) • Fever ... #hematology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Clinical Features: Fever ... : ↑↑ ferritin, Anemia ... IL-2 receptor Diagnostic ... 8 criteria: • Fever ... #hematology #criteria
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