86 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... Microangiopathy #thrombocytopenic ... #Comparison #Diagnosis ... #Table #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... and Acute Fatty Liver ... Bloodman #Pregnancy #Thrombocytopenia ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Hemolysis, Elevated Liver ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... Thrombocytopenic ... TTP Thrombotic #Thrombocytopenic ... #rheumatology # ... hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... mountain spotted fever ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... Diagnosis #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Clinical Features: Fever ... ferritin, Anemia, Thrombocytopenia ... 8 criteria: • Fever ... Lymphohistiocytosis #diagnosis #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... pulmonary edema) • Fever ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
megaloblastic anemia Treatment ... if neutropenic fever ... diagnosis #management #treatment ... #hematology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
purpura presents in thrombocytopenic ... petechiae/purpura with fever ... petechiae/purpura with fever ... likely to have thrombocytopenia ... #Diagnosis #Dermatology