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diagnosis management cardiology hematology differential syndrome activetb effusion erythematosus infectiousdiseases latenttb pericardial sle systemic tb tuberculosis activation apml boop causes
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: Fever ... effusion, Restrictive lung ... Pericarditis, Endocarditis ... symptoms #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... rash) • Heart, lung ... ALT ↑ bilirubin level
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework IATROGENIC DISEASE Secondary to invasive cardiac procedures NONIATROGENIC • Malignancy (e.g., metastatic spread:
metastatic spread: lung ... breast cancer, lymphoma ... Mediterranean fever ... induced • MCTD, Lupus ... especially those with lymphoma
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Non-autoimmune rheumatologic ... Angioimmunoblastic T-cell lymphoma ... • Libman-Sacks endocarditis ... to: Arthritis, Fever
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Non-Infectious: • Rheumatologic ... Mediterranean Fever ... - Metastatic: Lung ... Malignant - Primary: Lymphoma ... Diagnosis #Causes #cardiology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Treatment • Early ... cycles without XR ... classification #hematology ... #oncology #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... common • Imaging: CXR ... Renal Failure Treatment ... #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
characterized by fever ... Disorder: - Fever ... Symptoms: - Fever ... arthralgia) - Fever ... ’s syndrome - Lupus
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Neutropenic fever ... : - Fever + ANC ... interventional radiology ... or HSCT - CRS: fever ... therapy - Symptoms: fever
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... manifestations, hypoxia, CXR ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology ... #Oncology #Diagnosis
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