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diagnosis injury management nephrology classification differential hepatology liver rheumatology syndrome aclf algorithm apml cancer cell chronic cirrhosis dermatology differentiation diuresis
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... Methotrexate • AIN ... #AKI #Cancer #Oncology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... duration), Several medications ... non-essential drug/HDS treatments ... dechallenge • Acute ... Diagnosis #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Circulation Failure Kidney ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... Acute Kidney Injury ... , tenofovir • AIN ... #Acute #Kidney ... #Drugs #pharmacology
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... cardiorenal syndrome) • Liver ... nephritis (AIN) ... tract infection • Medications ... #Acute #Kidney
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... • AIN → Consider ... #Acute #Kidney
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Torsemide) • Acute ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... : • Common: fever ... effusions, weight gain ... diagnosis #management #hematology ... #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Inflammation and pain ... , breast CA - Hematologic ... Treatment: - Systemic ... #oncology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Metabolic syndrome • Medications ... swelling, significant pain ... nephrolithiasis, serum urate level ... • Serum urate level ... #rheumatology
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