12 results
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... Methotrexate • AIN ... #Oncology #Differential
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
and Pharmacology ... Inhibits plasminogen activation ... diarrhea & abdominal pain ... #Pharmacology # ... hematology
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... (AKI) - Management ... Treat underlying liver ... • AIN → Consider ... #Acute #Kidney
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
Dermatitis - Topical Treatment ... After non-pharmacologic ... has a different level ... #Medications #Pharmacology ... #Dermatology #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Heart, lung, and kidney ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... • Bicytopenia Treatment ... agent are the main ... diagnosis #management #treatment ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
malaise) - Muscle pain ... Inflammation and pain ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... effusions, weight gain ... Renal Failure Treatment ... diagnosis #management #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Antithyroid medications ... index < 2 • EPO Level ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Arthritis: • Joint pain ... C4) • ds-DNA: Kidney ... induced SLE • Kidney ... Chronic B-cell activation ... and/or medications