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diagnosis hematology management oncology table thrombocytopenia aflp anemia cppd gout hellp mds myelodysplastic obstetrics pregnancy ttphus activation acute apml autoimmune
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Presentation: • Fever ... index < 2 • EPO Level ... anemia Treatment ... Anemia #oncology #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... megaloblastic anemia Treatment ... if neutropenic fever ... Medicine @SCVMCMed #Aplastic ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... and Acute Fatty Liver ... Pregnancy (AFLP) Three syndromes ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Rheumatology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
production • Treatment ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... • Treatment: ... #Hyperthermia #comparison
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
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