13 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
nephritis can present ... abnormalities (non-nephrotic ... hematuria) • Frank nephritis ... (nephrotic-range ... suspicion for nephritis
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
CLINICAL • Nephritic ... syndrome (Casts ... proteinuria (may be nephrotic ... deposits common TREATMENT ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... nephritis, NPSLE ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... nephritis (LN) ... #Nephritis #Management ... #treatment #management
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
nephritis. ... SCLE, neonatal lupus ... overlap syndromes ... erythematosus #diagnosis ... #rheumatology #
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease Treatment ... #Summary #diagnosis ... #rheumatology # ... management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... #CNS #neurology ... #rheumatology # ... #management #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
nephritis, NPSLE ... Usual therapeutic management ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diagnosis of ... irrigation • Management ... kidney disease, and nephrotic ... kidney disease, and nephrotic ... Tolvaptan) • Treatment
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
experience Statin-Associated ... GBS), systemic lupus ... erythematosus (SLE ... Atorvastatin Diagnosis ... #management #treatment