11 results
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... #summary #table
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... High Aldosterone: Malignant ... • HTN Absent: Loop ... and thiazide diuretics ... #causes #potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... Clinicians should also look ... Post-hypercapnia • Diuretics ... Hyperaldosteronism: malignant ... causes #nephrology #potassium
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Elimination (see Table ... STOP offending medications ... (IV loop diuretic ... #potassium #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
training, Seizures, Malignant ... oxidative iniury Treatment ... Monitor potassium ... per day until stable ... Loop diuretics for
Treatment algorithm for malignancy-associated hypercalcemia
 • Aggressive IV hydration
 • IV Bisphosphonate +/- Calcitonin
 • Renal
Treatment algorithm ... for malignancy-associated ... Volume overload: Loop ... diuretic • Lymphoma ... #malignancy
Treatment algorithm for malignancy-associated hypercalcemia.
Hypercalcemia
 - Renal Failure → Dialysis with low Ca++ bath
Aggressive IV hydration
Treatment algorithm ... for malignancy-associated ... Volume Overload → Loop ... diuretic IV Bisphosphonate ... #algorithm #management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... +2Cl- Symport (Loop ... Tolvaptan) • Treatment ... #Pharmacology #Medications ... #Table
Pharmacologic Options for Hypercalcemia Associated with Cancer
Rehydration with NS followed by loop diuretics
 • IV normal
NS followed by loop ... diuretics • IV ... Inhibits vitamin D conversion ... management #drugs #treatment ... #pharmacology #table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Seizures - Malignant ... - Neuroleptic malignant ... Monitor potassium ... per day until stable ... Loop diuretics for