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diagnosis differential hypokalemia causes management treatment low pharmacology medications diuretics drugs hyponatremia metabolic rhabdomyolysis summary urine acei acidosis acute alkalosis
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... 90 minutes) • Sodium ... renal function) - Loop ... diuretic (often ... #nephrology
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP ... Chlorthalidone POTASSIUM-SPARING ... Pharmacology #summary #table ... #nephrology
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... Piretanide Potassium ... as no effect on sodium ... #Pharmacology #nephrology ... #conversion #loop
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... Clinicians should also look ... Post-hypercapnia • Diuretics ... #causes #nephrology ... #potassium
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Diagnosis Algorithm ... • HTN Absent: Loop ... and thiazide diuretics ... #causes #potassium ... #low #nephrology
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... algorithm Decreased ... • Drugs • Diabetic ... #Diagnosis #algorithm ... #nephrology #potassium
Algorithm for Management of Acute and Chronic Hyperkalemia Acute Hyperkalemia: - IV calcium (10 mL of 10%)
Algorithm for Management ... in 4 mL) - IV sodium ... therapy (loop diuretics ... mL/min) - Oral sodium ... Chronic #treatment #nephrology
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... Management of Hyperkalemia ... • SPS - Sodium ... #pharmacology #table ... #comparison #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... • Discontinued diuretic ... #nephrology #low ... #potassium
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
associated with hypokalemia ... overdose) - Sodium ... Furosemide and other loop ... diuretics ... differential #diagnosis #nephrology
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