19 results
Hypophosphatemia Diagnostic Algorithm
- GI Losses
- Redistribution
- 1° HPT
- 1° Renal PO4 wasting: Hereditary, TIO, Fanconi Syndrome,
Hypophosphatemia ... - 1° HPT - 1° Renal ... , TIO, Fanconi Syndrome ... #phosphorus #low ... #differential #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... can be high or low ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Workup for Hyperphosphatemia ... Rhabdomyolysis, Tumor lysis syndrome ... Kidney Disease: • AKI ... CKD Increased Renal ... Workup #phosphate #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... FEPO4 ≥ 5% - Renal ... • Normal or Low ... - Normal or Low ... Workup #phosphate #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... Epithelial Cells Renal ... of epithelial sodium ... #Kidney #Nephrology ... #Differential #Table
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Hypophosphatemia ... Appropriately Low ... Hyperparathyroidism, TKI ... , CAR-T cell #Hypophosphatemia ... Diagnosis #Algorithm #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... • Increased renal ... blood flow • ... hypertrophy • Sodium ... pathophysiology #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Na <20: Extra-renal ... Hypothyroidism, Low ... Cirrhosis, Nephrotic syndrome ... algorithm #diagnosis #sodium ... #low #nephrology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... blood flow: Pre ... renal AKI Idiosyncratic ... KidneyDisease #nephrology ... #renal
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
mOsm/kg - Implies renal ... • Euvolemic (Low ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium