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management lupus sle erythematosus oncology systemic syndrome algorithm cardiology chronic classification cll comparison disease druginduced foamed hemeonc leukemia lymphocytic neurology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus Clinical ... Serositis domain: Pleural ... pericarditis • Hematologic ... Erythematosus #diagnosis ... #rheumatology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
bleeding disorder Clinical ... prolonged if very low ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... • Pulmonary: pleural ... #management #treatment ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... 60-80% - Low ... life-threatening • Treatment ... Management #Summary #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... chemotherapy for low-risk ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... permeability Diagnosis ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... in >90% - Low ... sle #comparison #table ... #rheumatology # ... diagnosis #management
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Splenomegaly • Low ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
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