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diagnosis management signs hematology oncology pathophysiology endocrinology leukemia primary syndrome chronic cirrhosis clinical cll differential hepatology hiv neurology rheumatology workup
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... lymphadenopathy 3) B symptoms ... Splenomegaly 5) Symptoms ... chemotherapy for low-risk disease ... Constitutional symptoms
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... Findings B & T lymphocyte ... hyperplasia Note: B & T lymphocytes ... etiology Signs/Symptoms ... endocrinology #symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... extramedullary disease ... thrombocytosis) CML Symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting lymphocytes ... cell neoplasm • Lymphocytes ... with no early symptoms ... cells can indicate disease
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
the population Disease ... Autoimmune diseases ... and duration of symptoms ... angioedema Other symptoms ... infiltration (lymphocytes
Lyme Disease: Early and Late Clinical manifestations Stage 1. Localized • EM appears 7-14 days at the
Lyme Disease: Early ... neurologic SSX (lymphocytic ... WuidQ #Lyme #Disease ... diagnosis #signs #symptoms
Hansen's Disease (Leprosy) • Transmission - not completely understood, ?nasal droplets • Symptoms appear ~5 years
Hansen's Disease ... nasal droplets • Symptoms ... do not contract disease ... plasma cells, lymphocytes ... • Tuberculoid disease
Hashitoxicosis ‘Leakage’ symptoms of active Hashimoto’s disease - Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Hashitoxicosis ‘Leakage’ symptoms ... active Hashimoto’s disease ... of Hashimoto’s disease ... the thyroid by lymphocytes ... ‘Leakage’ symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
• Lymphocytic infiltration ... xeropthalmia) Mouth: • Lymphocytic ... interstitial lung disease ... pathophysiology #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... (SLE) Signs / Symptoms ... : - Lymphocyte ... Diagnosis #Signs #Symptoms
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