21 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ACLE) • Erythematous ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... /or medications
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... #Erythematosus ... #rheumatology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid ... - Indications and ... Pharmacology Pharmacokinetics ... #Indications #Pharmacology ... #hematology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... Excessive vomiting - Metabolic ... secretion • Acid-base ... components of acid-base ... Hypochloremia #Differential
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Chloride Algorithm Cl ... Kidney loss of Cl ... alkalosis • Loss of Cl ... Cystic fibrosis Cl ... Algorithm #nephrology #differential
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Erythematosus ... #medications #drugs ... #pharmacology # ... risk #differential ... #diagnosis #rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
and probably < ... Best indications ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... the face (many differential ... and aPL) 9) Unexplained ... clues #system #erythematosus ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... scleroderma) - Anti-Scl ... antibodies #diagnosis #rheumatology
Acid Base Disorders Worksheet

Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
Acid Base Disorders ... patient's alkalosis is metabolic ... patient's acidosis is metabolic ... - Cl - HCO3 > 12 ... joshsteinbergMD #Acid