18 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Anti-cardiolipin (aCl ... glycoprotein I (ß2GP), Lupus ... Anti-centromere, Scl
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
and probably < ... Best indications ... #rheumatology # ... pharmacology #levels ... #lupus #management
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Auto-Antibodies: - ANA ... ) 30-45% Differential ... Diagnosis and Lupus ... Lupusreference #SLE ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... erythematosus (ACLE ... permanent alopecia Differential ... La, anti-Jo-1, SCL ... /or medications
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... and aPL) 9) Unexplained ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... in drug-induced SLE ... scleroderma) - Anti-Scl ... antibodies #diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... ARUPConsult @ARUPLabs #ANA ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
family history - Medications ... function test, ANA ... (e.g., SLE), anti-phospholipid ... changes), high MCV ... not required in all
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... rubella titer, ACE ... protein) to exclude metabolic ... diagnosis #testing #Rheumatology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decreased metabolism ... ileal conduit - Medications ... Multiple myeloma, CML ... , AML - Large ... Hyperammonemia #Differential