9 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Action Along the Nephron ... AcuteKidneyInjury #AKI ... #Nephrology #Pathophysiology ... #Pharmacology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... release • ↓ Cl ... syndrome #Mechanisms #pathophysiology ... #nephrology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
filtered Na+/K+/Cl ... filtered Na+ and Cl ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
increase of 44 mol ... • Treatment includes ... #Vancomycin #AKI ... #pharmacology # ... diagnosis #management #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... loss through the nephron ... #Diuretics #Pharmacology ... #nephrology #conversion
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
declines > ALT) • AKI ... + myoglobin AKI ... urine output: 200 ml ... per day until stable ... #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... epilepticus Treatment ... underlying cause • Treatment ... diagnosis #management #neurology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Inhibitors of Na+K+2Cl ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, RTA Type IV, AI ... Elimination (see Table ... Ca-gluconate or 1g CaCl ... Redistribution Treatments ... #potassium #nephrology