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Causes of Hypercalcemia

#Differential #Hypercalcemia #Diagnosis #Causes #Endocrinology
Causes of Hypercalcemia ... #Differential ... #Hypercalcemia ... #Diagnosis #Causes ... #Endocrinology
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... #Causes #differential ... calcium #high #endocrinology
Causes of Hypercalcemia - Differential Diagnosis Algorithm
 • Primary Hyperparathyroidism 
 • Possible Familial Hypocalciuric Hypercalcemia
Causes of Hypercalcemia ... Hypocalciuric Hypercalcemia ... • Humoral Hypercalcemia ... DTomacruzM #Hypercalcemia ... #endocrinology
H’s and T’s Mnemonic - Causes of Cardiac Arrest
H's - Hypovolemia, Hypoxia, Hydrogen Ions (acidosis), Hyperkalemia
H’s and T’s Mnemonic ... - Causes of Cardiac ... Ions (acidosis), Hyperkalemia ... / Hypokalemia, ... #differential #
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Hypocalciuric Hypercalcemia ... Thiazides/Lithium #Hypercalcemia ... Diagnosis #Algorithm #causes ... #endocrinology
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... other hormonal causes ... uw_IMresidency #Hypercalcemia ... Diagnosis #algorithm #endocrinology
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... failure, acute or chronic ... Jansen disease #Hypercalcemia ... #Causes #Differential
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Myeloid Leukemia (CML ... Sarcoidosis • Hypercalcemia ... Diagnosis #Algorithm #endocrinology ... #causes
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Pheochromocytoma Chronic ... Milk-alkali syndrome #Hypercalcemia ... #Causes #endocrinology
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Hypernatremia - Differential ... hypercalcemia ... - Chronic hypokalemia ... #Diagnosis #Table ... #Causes