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diagnosis hematology algorithm syndrome neurology thrombocytosis anemia chronic disorders leukemia mds myelodysplastic nephrology pathophysiology syndromes acromegaly alcoholic aplastic apml basophilia
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Pseudotumor - Infectious ... History of Bleeding, Infection ... Fatigue • Acute ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... risk-stratification • Risks: infection ... transformation to acute ... #treatment #hematology ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... for workup, including ... Rebound effect from treatment ... : Chronic infections ... Thrombocytosis #Platelets #Differential
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... Thrombocytosis): • Acute ... infection • Solid ... myeloid leukemia (CML
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Myelofibrosis Infectious ... : • Acute or Chronic ... effect following treatment ... #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... myeloid leukemia (CML ... translocation • Acute ... #Diagnosis #causes ... #hematology #basophils
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... procedures - Infection ... changes), high MCV ... #Workup #hematology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
• HIV/HCV co-infection ... HBV infection with ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
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