41 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... and probably < ... (e.g. renal failure ... #rheumatology # ... levels #lupus #management
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
in drug-induced SLE ... scleroderma) - Anti-Scl ... • Sjögren syndrome ... Jcortesizaguirr #ANA ... antibodies #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Antinuclear (ANA ... severe disease & renal ... block • Sjogren syndrome ... Summary #diagnosis #rheumatology ... #management
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
AKI) What to ask ... /K/Cl/urea/protein ... rhabdo/TLS) Causes ... AcuteKidneyInjury #AKI #Nephrology ... Diagnosis #Algorithm #Causes
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
dL the ULN R - Renal ... Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
Renal involvement ... Combined decr of C3 and ... Cryoglobulinemia #Vasculitis #Management ... #Rheumatology # ... Cryoglobulinemic #Nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Management Summary ... iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... levels > 8mg/dL See ... #Summary #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary ... Causes of Rhabdomyolysis ... urine output: 200 ml ... #causes #treatment ... #nephrology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
aseptic meningitis), MCC ... Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management ... signs #symptoms #rheumatology