31 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... (0.5 - 0.8 ng/mL ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Massive Hemoptysis - Differential Diagnosis Framework and Management
Definition: 150-600 mL over 24 hours
Differential Diagnosis:
 • Tracheobronchial:
Diagnosis Framework ... Definition: 150-600 mL ... Primary Vascular: Pulmonary ... Management: 1) Indications ... #pulmonary #criticalcare
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
Common Medications ... #Prolongation #Medications ... #Causes #differential ... #diagnosis #pharmacology ... #table
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Diagnosis Framework ... Failure, Toxins/Medications ... • Obstructive: Pulmonary ... #algorithm #treatment
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Edema - Differential ... Diagnosis Framework ... NCPE Pathophysiology ... level <100 pg/ml ... #diagnosis #cardiology
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
tablet once daily ... increase to 500 mcg ... recommendations for the treatment ... the use of this medication ... #Pharmacology #
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Bloodman #Drugs #medications ... Hemolytic #Anemia #differential ... #diagnosis #pharmacology ... #table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment ... Reactions #hematology #diagnosis ... #comparison #table
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... shows a small, stable ... Lung Abscess Differential ... Lung #Abscess #pulmonary ... #differential #