25 results
Iron Deficiency in Congestive Heart Failure (CHF)

Iron deficiency (ID) in heart failure is a common comorbidity
Heart Failure (CHF ... Ferritin < 100 ng/mL ... depot iron] Treatment ... #pharmacology # ... pathophysiology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Syndrome - Causes and Treatment ... transformation (CML ... Phlebotomy - MH/CCF ... Syndrome #Causes #Differential ... #Diagnosis #Treatment
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... Ferritin <100 ng/mL ... Ferritin 100-299 ng/mL ... functional ID) Treatment ... iron #deficiency #CHF
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... : Age>60, CKD, CHF ... : No • Treatment ... Transfusion #Reactions #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... sepsis), PE, DAH, CHF ... diagnosis #management #hematology
Tachypnea - Differential Diagnosis Framework

Definitions
 • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults
 •
Tachypnea - Differential ... Pneumonia • CHF ... effusion/Tamponade Hematologic ... Post-Ictal/Grand mal ... Tachypnea #Hyperpnea #Differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Responsive to Treatment ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
decompensation (CHF ... hyperparathyroidism Treatment ... Syndrome #Nutrition #Differential ... #Diagnosis #Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... sIL-2R >2400 Ul/ml ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology