31 results
diagnosis hematology causes management anemia druginduced lupus monoclonal sle algorithm comparison drugs erythematosus hodgkins lymphoma mgus pathophysiology systemic thrombocytosis ammonia
Raynaud Phenomenon Differential Diagnosis: Rheumatologic - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD Heme -
Raynaud Phenomenon Differential ... Diagnosis: Rheumatologic ... - MCC systemic ... , SLE, Sjogren syndrome ... #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... Thrombocytosis #Platelets #Differential
Serotonin Syndrome Drug Precipitants and Pharmacology ↑ Serotonin Formation: Tryptophan, Oxitriptan ↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine ↑ Serotonin
Serotonin Syndrome ... Precipitants and Pharmacology ... #Pharmacology # ... medications #causes ... #differential #
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
/dL or CC < 40 ml ... M spike: • CML ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... probably < 1500ng/mL ... Best indications ... Measurement #SLE #rheumatology ... #pharmacology #
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Myelodysplastic syndrome ... myeloid leukemia (CML ... Thrombocytosis #Differential ... Diagnosis #Causes #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
) Low MCV - <80fL ... anemia" High MCV ... Myelodysplastic syndrome ... #differential # ... diagnosis #causes #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & MBL ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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