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management hematology differential gammopathy oncology algorithm disease multiplemyeloma neurology rheumatology nephrology significance acute agglutinin aki al allergy amyloid anemia angioedema
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... (MGUS) - Differential ... capillary leak syndrome ... Renal-centered (ie "MGRS ... #Significance #MGUS
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... • MGCS • MGRS ... ) MGRS: • Fibrillar ... deposits: • Amyloidosis ... #Differential #Diagnosis
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS) Mayo Clinic Risk Stratification Model. CBC,
for follow-up of monoclonal ... significance (MGUS ... ) Mayo Clinic Risk ... #MGUS #Followup ... #algorithm #diagnosis
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... whom there are no clinical ... algorithm #diagnosis
Amyloidosis Diagnosis 1) Patient presentation • Cardiac-specific signs of amyloidosis: Diastolic heart failure, Heart failure with preserved
Amyloidosis Diagnosis ... and diarrhea, Monoclonal ... significance (MGUS ... neuropathy, atypical MGUS ... #Diagnosis #cardiology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... Light-Chain MGUS ... not defined #MGUS
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
deposition disease, and amyloidosis ... diseases, CML, amyloidosis ... plasmacytoma, POEMs syndrome ... #Gammopathies #MGUS ... #diagnosis #hematology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
tubulopathy • Monoclonal ... significance (MGRS ... malignancies Treatment ... Capillary leak syndrome ... #Differential #Diagnosis
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... antibody - Early treatment ... rituximab (in clinical ... high-risk situations #MGUS ... Complications #diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... Myeloma • MGUS ... • Fanconi's syndrome ... Amyloidosis) ... #Differential #Diagnosis
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