17 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... Kidney Injury - ... the Nephron #DrugInduced ... AcuteKidneyInjury #AKI #Nephrology ... Pathophysiology #Pharmacology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
renal failure • Drugs ... uropathies • Drugs ... hyperplasia • Drugs ... nephropathy • Drugs ... #potassium #differential
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Kidney Injury ( ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications ... #druginduced
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Glomerular Disease: Drug ... @kdjhaveri #DrugInduced ... #KidneyInjury #differential ... diagnosis #algorithm #nephrology
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Kidney Injury ( ... tubular necrosis • Drugs ... nephritis • Drugs ... Postrenal #Failure #Differential ... #Nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
- Differential ... systemic disease or drugs ... hypotension • Drugs ... Nephritis (AIN) • Drugs ... #Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... (AKI) - Differential ... Infection-mediated, Drug-induced ... #Kidney #Injury ... Diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
) - Differential ... syndromes • Drugs ... (E. coli) • Drugs ... Nephritis • Drugs ... #KidneyInjury #Nephrology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Drug induced ... acute kidney injury ... 24-72 hours of drug ... Vancomycin #AKI #pharmacology ... diagnosis #management #nephrology