22 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... atypical HUS) - Drug-induced ... #schistocytes #differential ... #diagnosis #hematology ... #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... infection) - Drugs ... (Beta lactam antibiotics ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential ... delayed HTR • Drug-induced ... • PNH • Drug-induced ... Extravascular #Differential ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Transfusion reactions, Drug-associated ... Membrane Defects, Drugs ... #Differential # ... Diagnosis #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Approach to Anemia - Differential ... -100): • Non-hemolytic ... anemia, CKD • Hemolytic ... Orotic aciduria, Drugs ... #Diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... • Bleeding • Hemolysis ... Deficiency • Drugs ... Classification #Differential ... Algorithm #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... AIHA: warm, cold, drug ... #Anemia #Differential ... classification #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Secondary Causes: - Drug ... DIC/TTP/HUS - Hemolytic ... spotted fever • Drug ... #Diagnosis #hematology ... #rheumatology #
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
suppression (e.g. drugs ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential
Drug Induced Uveitis - Medications Associated with Uveitis

#DrugInduced #Uveitis #Medications #Rheumatology #Pharmacology #Differential #Causes
Drug Induced Uveitis ... #Medications #Rheumatology ... #Pharmacology # ... Differential #Causes