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Clinical Manifestations of Systemic Lupus Erythematosus (SLE) #Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... Erythematosus (SLE ... Erythematosus #SLE ... #Manifestations
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... 1 • Clinical Manifestations ... are evocative of SLE ... • Laboratory Manifestations ... management of SLE
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... Infectious manifestations ... Autoimmune manifestations ... dermatomyositis, SLE ... #Cutaneous #manifestations
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... M • Clinical Manifestations ... • Laboratory Manifestations ... Erythematosus (SLE ... are evocative of SLE
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Musculoskeletal Manifestations ... Erythematosus #SLE
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Associated with skin manifestations ... • Neonatal SLE ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... Erythematosus #SLE
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE ... ) Clinical Manifestations ... Erythematosus #SLE
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... Phenomenon #Lupus #SLE ... Mucocutaneous #Manifestations
Infective Endocarditis - Diagnosis and Management Summary Pearls: - Consider non-infectious endocarditis in pts with cancer/SLE and
pts with cancer/SLE ... nodes are rare manifestations
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