23 results
differential algorithm oncology causes management dermatology pruritus systemic treatment chronic cll generalized lymphocytic mds myelodysplastic pancytopenia rheumatology secondary thrombocytopenia arthritis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Diagnosis: • Pancytopenia ... to MDS or acute leukemia ... #Anemia #diagnosis ... management #treatment #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Leukemia, Tumour ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... Chronic Myelogenous Leukemia ... Iron deficiency anemia ... #Differential #Diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... marrow failure: Aplastic ... Production #Index #hematology ... #diagnosis #calculation
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... • Neutropenia, anemia ... Pure red cell aplasia ... #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... mutations) • Immune Aplastic ... virus (EBV) • Leukemia ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... transformation to acute leukemia ... Management #treatment #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Algorithm #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... all phases of maturation ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
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