26 results
Algorithm for screening/diagnosis and treatment/follow‐up of iron deficiency in patients with chronic heart failure. Hb, haemoglobin;
/diagnosis and treatment ... follow‐up of iron deficiency ... TSAT, transferrin saturation ... #Iron #Deficiency ... #Treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Acute hemolysis, deficiency ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... • Reaction to Medications ... : Chronic infections
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron deficiency ... (e.g. cancer, infection ... cell anemia, G6PD deficiency
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelofibrosis Infectious ... effect following treatment ... malignancy • Iron deficiency ... Algorithm #Causes #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Cellular immune deficiency ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... Cystic fibrosis • Medications ... dental fixatives, Treatment ... Stroke, Myocardial infarction ... drkeithsiau #Copper #Deficiency
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
disease • Iron-deficiency ... unresponsive to treatment ... Autoimmune • CVID • Medications ... NSAlDs, ARBs) • Infection
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm INDICATIONS ... drug reaction, infection ... Strongyloides infection ... glucocorticoid treatment ... Differential #diagnosis #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Diaqnoses: • Infectious ... mevalonate kinase deficiency ... diagnosis #management #treatment ... #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
anemia, GATA2 deficiency ... , CTLA4 deficiency ... - Antithyroid medications ... Idiopathic • Infections ... aplastic anemia Treatment