118 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... inflammation • Thrombocytopenia ... Primary Causes: - Thrombocytopenia ... #Differential #Diagnosis ... #hematology #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... disorders • Celiac disease ... effect following treatment ... following EtOH induced thrombocytopenia ... Algorithm #Causes #Hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... Microangiopathy #thrombocytopenic ... #Comparison #Diagnosis ... #Table #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic ... Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... #rheumatology # ... hematology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of Vasculitis ... Vasculitis of ... #Vessels #Diagnosis ... #Rheumatology # ... Diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Algorithm Thrombocytopenia ... • Steroids • Vasculitis ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... HUS • DIC • Vasculitis ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... , Vasculitides, ... IBD, Celiac disease ... #Algorithm #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... platelet count (mild thrombocytopenia ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
, Rheumatoid Vasculitis ... Rheumatoid Nodules, Pulmonary ... Disease and ILD ... Arthritis #RA #diagnosis ... #rheumatology #