34 results
differential algorithm hemolytic management workup causes syndrome atlas chronic cll extravascular hepatology intravascular leukemia liver lymphocytic monoclonal morphology rheumatology signs
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... : • Autoimmune ... • Extrinsic RBC ... • Intrinsic RBC ... #hematology
Pathophysiology of Hemolytic Anemia - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects) -
of Hemolytic Anemia ... - Defects in RBC ... - Defects in RBC ... #Hemolytic #Anemia ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... Hemolytic Anemia ... 1) DIAGNOSE AIHA ... ↑ LDH • Anti-RBC ... #Hemolytic #Anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Bleed • Hemolysis ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... hemolytic anemia ... hemolytic anemia ... #differential #diagnosis ... #hematology #microscopy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... • Intrinsic RBC ... #differential #diagnosis ... #hematology #anemia
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Membrane): - Autoimmune ... 3) Internal (RBC ... Defects: Sickle cell anemia ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... anemia • ... Algorithm #Causes #Hematology
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... , Hemolytic anemia ... Sickle cell, MDS #RBC ... Inclusions #Bodies #diagnosis ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... elliptocytosis, autoimmune ... #workup #hematology
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