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diagnosis differential treatment oncology algorithm causes disease erythematosus hemolytic lupus pancytopenia signs sle symptoms systemic aplastic gout hemolysis hemophagocytic hlh
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Marrow Failure Syndromes ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... #diagnosis #Hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Features: alveolitis, ear ... vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... suspect underlying hematologic ... #HES #Hematology ... eosinophils #diagnosis #management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Sideroblastic anemia ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... #differential #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #treatment #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... Gastrectomy, WHDA syndrome ... diet, Alcoholism, Tea-toast ... Iron #Deficiency #Anemia ... Algorithm #ferritin #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... Autoimmune #Hemolytic #Anemia ... #diagnosis #management ... #treatment #rheumatology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
hemolytic-uremic syndrome ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... differential #diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... thalassemia • Anemia ... Normocytic" • Anemia ... Myelodysplastic syndrome ... diagnosis #causes #hematology
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