12 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... #Binding #KBinders ... Kayexelate #Comparison #Table ... #Pharmacology # ... #HyperKalemia #Nephrology
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
- Calcium and metal-free ... - Calcium and metal-free ... #Table #Comparison ... #Pharmacology # ... Nephrology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... #Binders #Management ... Hyperkalemia #treatment #pharmacology ... #table #comparison ... #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Chlorthalidone POTASSIUM-SPARING ... #Diuretics #Medications ... #Pharmacology # ... summary #table # ... nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #Hyperkalemia #medications ... #pharmacology # ... table #comparison
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... - Useful for short ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology #
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
drug-antibody complex binds ... Bloodman #Drugs #medications ... #differential #diagnosis ... #pharmacology # ... table
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
retention • Binds ... Edrophonium • Used for diagnosis ... blockers • Has short ... Cholinergic #Agonists #Pharmacology ... #Table #Summary
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... fluid/Lactated ringers ... Monitor potassium ... per day until stable ... #Differential #Diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Elimination (see Table ... STOP offending medications ... Management #Treatment #potassium ... #nephrology #K