49 results
Melanoma Treatment Algorithm

Resectable vs Inoperable Disease

Matthew Ho, MD PhD @MatthewHoMD and Aakash Desai, MD @ADesaiMD

#Melanoma #Treatment
Melanoma Treatment ... vs Inoperable Disease ... #Treatment #Algorithm ... #Management #dermatology ... #oncology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... solid cancers • Systemic ... #diagnosis #management ... #treatment #rheumatology
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
an underlying systemic ... disease ... Muehrcke's Lines • Melanoma ... fingernail #pathology #differential ... #diagnosis #dermatology
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
an underlying systemic ... disease ... Muehrcke's Lines • Melanoma ... fingernail #pathology #differential ... #diagnosis #dermatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... #rheumatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Ig deposition disease ... #Diagnosis #hematology ... #oncology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... for workup, including ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
Systemic Therapy ... for Disease Progression ... #Treatment #Management ... #Hepatology #Gastroenterology ... #oncology #Pharmacology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia 1) DIAGNOSE ... • Blood smear: Differential ... FOR a cause → Systematic ... #management #treatment ... #rheumatology