14 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... decreased PLT count: CBC ... peripheral blood smear, HIV ... (CVID, WAS), (neurologic ... #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... cells per μL • Diagnosis ... Antimicrobial treatment ... Demyelinating disease caused ... #differential #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 2 hit mechanism ... without other cause ... : 33% • Treatment ... : No • Treatment ... #diagnosis #comparison
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Treatment: • ... #management #treatment ... #summary #rheumatology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... Diagnosis: MRI ... and with low CD4 ... Treatment: • HAART ... dementia #AIDS #Neurology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... : • CBC - Leukocytosis ... hemorrhage • Treatment ... #differential #causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... deficiency) • HIT ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Campylobacter jejuni - HIV ... Guillain-Barre Diagnosis ... #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
- Emergency Causes ... Differential Diagnosis ... cord infarct • HIV ... axial T1 and T2 Treatment ... #causes #neurology