10 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
of Abnormal Coagulation ... Tests - Prolonged PT ... and Prolonged PT ... APTT #Laboratory #Hematology ... #Diagnosis #Workup
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged PT ... • Prolonged PT ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
initiation of fibrin clot ... achieve 20 mm clot ... Thromboelastogram #TEG ... Thromboelastography #diagnosis ... #coagulation #hematology
THROMBOELASTOGRAPHY (TEG)
General Principle
• A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
THROMBOELASTOGRAPHY (TEG ... problems with coagulation ... @nickmmark #TEG ... Thromboelastography #Diagnosis ... #CriticalCare #Hematology
Normal Thromboelastogram - Specific parameters represent the 3 phases of the cell-based model of haemostasis: initiation,
certain level of clot ... of the fibrin clot ... (s) #Diagnosis ... #Hematology #Coagulation ... Thromboelastogram #TEG
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
platelet aggregation PT ... using INR use PT ... thrombin to form clots ... ISTH #Scoring #diagnosis ... #hematology #laboratory
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... platelet #thrombin #clot ... #PT #PTT #diagnosis ... #models #hematology ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... protein C and S Pathophysiology ... significant fibrin clot ... #diagnosis #causes ... treatment #management #hematology
Thromboelastography (trademarked as TEG)
 • Graphical representation of the fibrin polymerization process
 • Point-of-care anti-coagulation monitoring
trademarked as TEG ... Point-of-care anti-coagulation ... routine transfusion algorithms ... elapsed until clot ... interpretation #hematology
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
is a product of clot ... indicate that coagulation ... Ddimer #dimer #pathophysiology ... #hematology #differential ... #diagnosis #age