39 results
Anemia - Hemolysis Diagnostic Algorithm
Autoimmune hemolytic anemia
Microangiopathic hemolytic anemia
Probable thalassemia

Dr. Eric Strong @DrEricStrong - Strong Medicine
Anemia - Hemolysis ... anemia Microangiopathic ... hemolytic anemia ... EricsMedicalLectures/ #Hemolysis ... hematology #diagnosis #differential
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... of anemia and hemolysis ... Immune-mediated Hemolysis ... Nonimmune-mediated Hemolysis ... Macroangiopathic, Microangiopathic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... Extravascular Hemolysis ... EricsMedicalLectures/ #Hemolysis ... Extravascular #Causes #differential
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... fragmentation hemolysis ... Drug-induced thrombotic microangiopathy ... • Mechanical hemolysis ... diagnosis #hematology #hemolysis
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... - Differential ... Immune mediated hemolysis ... Schistocytes DAT(-) → Microangiopathic ... #Anemia #Differential
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... Often hard to differentiate ... implications : TTP has high ... thrombocytopenia #Comparison ... #Diagnosis #Table
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... ischemia-induced RBC hemolysis ... ) • RBC Hemolysis ... TTKG should be high ... causes #potassium #high
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... Bleed • Hemolysis ... Fragments • Microangiopathic ... Hemolytic Anemias ... Normocytic #Anemia #Differential
Causes of Cough and Hemoptysis
Acute Inflammation 
 - Laryngitis 
 - Tracheobronchitis 
 - Mycoplasma and
Causes of Cough and Hemoptysis ... Chronic #Cough #Hemoptysis ... #Differential # ... Causes #Table
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
• Present in high ... bloodstream Hemolysis ... - Acquired: Microangiopathic ... , PNH, immune hemolysis ... myelofibrosis • Hemolysis