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diagnosis causes hemolytic aflp anemia hellp obstetrics pregnancy rheumatology thrombocytopenia ttphus vasculitis workup anemias clinicopathology dili diseases disorders drug extravascular
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm ... Extrinsic RBC Defects ... Intrinsic RBC Defects ... : Membrane defects ... #hematology
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
vessel vasculitis affects ... predominantly affects ... predominantly affects ... #Differential # ... Medium #Large #Classification
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... Abnormal Hgb & Hgb Defects ... Hgb - Membrane Defects ... - RBC Enzyme Defects ... #Causes #Hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Qualitative Platelet Defects ... Inherited #Platelet #Defects ... #comparison #table ... #differential # ... diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... , Other enzyme defects ... Unstable hemoglobin defects ... Glutathione metabolism defects ... #workup #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
with coagulation defects ... Severe coagulation defects ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
with coagulation defects ... Severe coagulation defects ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... • Membrane defects ... Hemolytic #Anemia #Differential ... Diagnosis #causes #classification ... #hematology
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
- Genetic defects ... Hypomagnesemia #Differential ... Low #Magnesium #Table ... #Classification
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
less common, only affects ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
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