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diagnosis differential anemia causes hemolysis management table aflp extravascular hellp intravascular obstetrics pregnancy thrombocytopenia ttphus : advancedcopd anemias blvr bullectomy
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... Extrinsic RBC Defects ... Intrinsic RBC Defects ... : Membrane defects ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... Abnormal Hgb & Hgb Defects ... Hgb - Membrane Defects ... - RBC Enzyme Defects ... #Causes #Hematology
Pathophysiology of Hemolytic Anemia - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects) -
Anemia - Defects ... and metabolic defects ... ) - Defects in ... rnembranes - Defects ... #Anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... , Other enzyme defects ... Unstable hemoglobin defects ... Glutathione metabolism defects ... #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... Intrinsic RBC Defects ... thalassemias), Membrane defects ... differential #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Non-immune: Membrane Defects ... Spiders - Enzyme Defects ... - Hemoglobin Defects ... Differential #Diagnosis #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
with coagulation defects ... . 1) HELLP (Hemolysis ... Severe coagulation defects ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
with coagulation defects ... . 1) HELLP (Hemolysis ... Severe coagulation defects ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Thrombocytopenia • Platelet defects ... PURPURA: Platelet Defects ... DIC/TTP/HUS - Hemolytic ... syndrome Coagulation Defects ... Differential #Diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... • Membrane defects ... udaygulati #Hemolytic ... classification #hematology
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