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Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... of Systemic Lupus ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
- Differential Diagnosis ... migrans: • Target sign ... gabrieltalledop #dermatology ... #differential #diagnosis ... #peds #pediatrics
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #differential #diagnosis ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Erythematosus Clinical ... pericarditis • Hematologic ... Erythematosus #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Diagnosis Manifestations ... Differential Diagnosis ... Erythematosus #Diagnosis ... autoantibodies #signs ... #differential #rheumatology
Lupus is diagnosed using clinical and laboratory diagnostic criteria set by the American College of Rheumatology.
Lupus is diagnosed ... using clinical ... American College of Rheumatology ... A diagnosis of lupus ... #Diagnosis #Rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... Immunologic Criteria CLINICAL ... hemolytic anemia #Diagnosis ... #Rheumatology #
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... #Systemic #Lupus ... #SLE #Summary #diagnosis ... #rheumatology #
Dermatofibroma 
 - Skin-colored to brown papule or nodule 
 - Firm, indurated texture 
 -
Dermatofibroma - Skin-colored ... Male - Dimple sign ... Dermatofibroma #Dermatology ... #Diagnosis #Benign ... #Clinical #Photo